![]() The practical consequence was an extremely positive fluid balance in order to maintain blood volume during major surgery. Therefore, perioperative fluid regimens were traditionally based on a generous replacement of this assumed primary loss, in addition to deficits due to insensible perspiration and fasting. So anyway- here is some peer reviewed information regarding the vascular spaces we deal with □įor decades, the ‘third space’ was looked upon as an actively consuming compartment. It’s always cool (and almost glib) to nonchalantly dump out the phrase- “the pt is thrid spacing” as an explanation for where our volume might be hiding, or for obvious signs of tissue edema (puffy or swollen faces/hands and feet). I was chatting with the surgeon while he was taking down the IMA, and mentioned that while I was familiar with the concept of “third spacing”, I needed to clarify the implied “first”, and “second” spaces. ![]() Part of what we do involves some major fluid shifts within the patient as a result of our prime constituents, pharmacological additives administered during the pump run, and the ability of the human body to physiologically compensate for dynamic fluid shifs and variances in Colloidal Osmotic Pressure (COP). “While I was familiar with the concept of “third spacing”, I needed to clarify the implied “first”, and “second” spaces.”īack quite a while ago, I was really into publications, and the academic side of cardiac perfusion and education.
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